Actively Recruiting
Personalized Anticoagulant Treatment for Pulmonary Thromboembolism in Older Adults, Patients with Kidney Problems, or Cancer
Led by Xiangya Hospital of Central South University · Updated on 2024-04-02
4700
Participants Needed
1
Research Sites
52 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are examining how anticoagulant therapy works for people with pulmonary thromboembolism PTE, especially focusing on older adults, those with kidney problems, or cancer. The study aims to find factors that affect the treatments safety and success, and to develop machine-learning models to predict bleeding events and recurrence of blood clots in these special groups. Participants will receive care for PTE following clinical guidelines, including anticoagulant treatment decided by their doctors. Some participants will have blood samples taken at the start and three months after starting therapy to support research. This is an observational study, so treatments are not assigned by the researchers but recorded as they happen in real life. Throughout the study, participants will be monitored for any major or clinically relevant bleeding and for blood clot recurrence over 12 months after starting treatment. Researchers will also track overall survival during this time. Participants must agree to regular follow-ups and provide consent, with the total observation lasting up to one year after treatment begins.
CONDITIONS
Brief Title
Personalized Anticoagulant Therapy for Pulmonary Thromboembolism
Research Team
P
Pengbo Deng, MD
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