Actively Recruiting
Personalized B-fructan Diet in Inflammatory Bowel Disease Patients
Led by University of Manitoba · Updated on 2025-04-06
600
Participants Needed
2
Research Sites
121 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to examine patient tolerability of personalized dietary fibre consumption recommendations (high-pectin diet versus high-B-fructan diet based on personalized responses), provided by an IBD dietician, based on our novel translational research findings.
CONDITIONS
Official Title
Personalized B-fructan Diet in Inflammatory Bowel Disease Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children aged 6 to 17 years or young adults aged 18 to 39 years
- Known or suspected ulcerative colitis or inflammatory bowel disease unclassified
- For ulcerative colitis: remission to moderate disease with a Mayo score less than 10
- Clinical indication for sedated colonoscopy
- Disease location between E2 and E4
- Stable treatment without steroids; no changes in biologics or immunomodulators in the last month
- High likelihood of ability to collect all samples and provide all required data
You will not qualify if you...
- Use of antibiotics for one week or more in the last 3 months
- Use of probiotics or prebiotics at pharmacological doses (adding fiber sources to food or probiotics in yogurt is allowed)
- History of abdominal surgery, including appendectomy
- Documented enteric infection within 3 months before endoscopy
- Presence of non-IBD bowel conditions, anatomical or mucosal abnormalities, or motility disorders
- Presence of systemic diseases requiring treatment, such as cancer, ischemic heart disease, or kidney failure
- Proctitis (E1 disease location)
- Use of systemic steroids above 10 mg/day of Prednisone
- Use of topical therapy within 1 week of endoscopy
- Recent changes in IBD treatment (started biologics or immunomodulators in the last month)
- Pregnancy or planning pregnancy during the study
- Inability to understand or sign the consent form
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
University of Alberta Hospital
Edmonton, Alberta, Canada, T6G 1C9
Actively Recruiting
2
Health Sciences Centre Hospital
Winnipeg, Manitoba, Canada, R3E 3P4
Actively Recruiting
Research Team
H
Heather Armstrong, MSc, PhD
CONTACT
E
Eytan Wine, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
4
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