Actively Recruiting
Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB)
Led by Senthil Sadhasivam · Updated on 2026-04-13
300
Participants Needed
5
Research Sites
266 weeks
Total Duration
On this page
Sponsors
S
Senthil Sadhasivam
Lead Sponsor
N
National Institute on Drug Abuse (NIDA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this collaborative CTSA application is to develop an innovative perioperative precision analgesia platform (PPAP) to improve analgesia and reduce serious immediate and long-term adverse outcomes of perioperative opioids in children undergoing painful surgery.
CONDITIONS
Official Title
Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children ages 10 to 21
- ASA physical status 1 to 3
- Undergoing Posterior-Lateral Spinal Fusion
- Receives in-patient opioids
- Prescribed opioids at discharge
You will not qualify if you...
- Serious illness
- Preoperative severe pain
- Preoperative opioid use or misuse
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
University of California
San Francisco, California, United States, 38456
Actively Recruiting
2
Children's Orthopaedic and Scoliosis Surgery Associates, LLP
St. Petersburg, Florida, United States, 33701
Not Yet Recruiting
3
Johns Hopkins All Children's Hospital
St. Petersburg, Florida, United States, 33701
Not Yet Recruiting
4
Riley Children's Hospital
Indianapolis, Indiana, United States, 46202
Actively Recruiting
5
UPMC Children's Hospital
Pittsburgh, Pennsylvania, United States, 15224
Actively Recruiting
Research Team
S
Senthilkumar Sadhasivam, MD, MPH
CONTACT
D
Dayana Alsamsam, BSPS, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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