Actively Recruiting
Personalized Postoperative Pain Management Following Thoracic Surgery in Adults
Led by OpalGenix, Inc · Updated on 2025-05-01
200
Participants Needed
4
Research Sites
221 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research. This research focuses on two of the most commonly used oral opioid analgesics, oxycodone, and methadone, in adults following thoracic surgery. Major inpatient thoracic surgeries (TS) for lung disease are common and extremely painful surgeries and are associated with sever post-surgical pain, high incidence of chronic post-surgical pain (CPSP), excess opioid use, costly immediate postoperative opioid adverse events (AEs), and long hospital stays. This study is aiming to develop proactive risk prediction algorithms for precision surgical pain relief in adult TS patients through comparison of actual clinical outcomes with standard of care to predicted outcomes based on personalized risk assessments.
CONDITIONS
Official Title
Personalized Postoperative Pain Management Following Thoracic Surgery in Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age greater than 18 years
- American Society of Anesthesiologists (ASA) Physical Status 1, 2, or 3
- Undergoing thoracic surgery including pneumonectomy, lobectomy, or segmentectomy
You will not qualify if you...
- Under 18 years of age
- Pregnant women
- American Society of Anesthesiologists (ASA) Physical Status 4 or higher
- Non-English speaking
- Outpatient surgery
- Additional surgical procedures combined with thoracic surgery
- Significant liver or kidney dysfunction
- Significant cardiorespiratory compromise
- Current polysubstance use such as cocaine, marijuana, or amphetamines
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
UPMC Presbyterian Hospital
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
2
UPMC Mercy Hospital
Pittsburgh, Pennsylvania, United States, 15219
Actively Recruiting
3
UPMC Shadyside Hospital
Pittsburgh, Pennsylvania, United States, 15232
Actively Recruiting
4
UPMC Passavant Hospital
Pittsburgh, Pennsylvania, United States, 15237
Actively Recruiting
Research Team
A
Amy Monroe, MPH, MBA
CONTACT
A
Alisha Maslanka, BS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here