Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT04735835

Personalized Responses to Dietary Composition Trial 3

Led by Zoe Global Limited · Updated on 2025-04-16

250000

Participants Needed

2

Research Sites

493 weeks

Total Duration

On this page

Sponsors

Z

Zoe Global Limited

Lead Sponsor

M

Massachusetts General Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

The PREDICT 3 study will build on previous research in over 2,000 individuals to further refine machine learning models that predict individual responses to foods, with the aim of advancing precision nutrition science and individualized dietary advice. The study incorporates both standardized and controlled dietary intervention, for the purpose of testing postprandial responses to specific mixed meals, in addition to a free-living period with a dietary record for measuring responses to a large variety of meals consumed in a realistic context, where the role of external factors (e.g. exercise, sleep, time of day) on postprandial responses may be determined. For the first time this PREDICT study is built on top of a commercial product which will allow access to a much larger group of participants who are already collecting large amounts of data through digital and biochemical devices that can contribute to science.

CONDITIONS

Official Title

Personalized Responses to Dietary Composition Trial 3

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Enrolled in the commercial ZOE testing program
  • Any sex
  • Minimum 18 years of age (minimum 19 years in Alabama and Nebraska)
  • Body mass index (BMI) of at least 16.5 kg/m2
  • Living in continental US states (except New York) or in the UK
  • Able and willing to follow the study protocol and give informed consent
  • Under care for chronic medical conditions and have checked with their primary care physician that the study is safe (US cohort only)
Not Eligible

You will not qualify if you...

  • Unable or unwilling to safely eat the pre-made test meals containing standard US ingredients
  • Pregnant
  • Had a heart attack, stroke/transient ischemic attack, or major surgery in the last two months
  • Unable to read and write in English (ZOE app is only available in English)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Zoe US Inc.

Needham, Massachusetts, United States, 02494

Actively Recruiting

2

King's College London

London, United Kingdom

Actively Recruiting

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Research Team

M

Meaghan Reardon

CONTACT

D

Dan Sleeper

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

PREVENTION

Number of Arms

1

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Personalized Responses to Dietary Composition Trial 3 | DecenTrialz