Actively Recruiting
Personalized Swiss Sepsis Study
Led by University Hospital, Basel, Switzerland · Updated on 2025-03-05
17500
Participants Needed
16
Research Sites
315 weeks
Total Duration
On this page
Sponsors
U
University Hospital, Basel, Switzerland
Lead Sponsor
S
Swiss Personalized Health Network (SPHN)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This multi-center study is to focus on patients with sepsis in Intensive Care Units (ICUs) in order to better understand the complex host-pathogen interaction and clinical heterogeneity associated with sepsis. Understanding this heterogeneity may allow the development of novel diagnostic approaches. Data from patients will be analyzed using state-of-the art analytical algorithms for biomarker discovery including machine learning and multidimensional mathematical modelling to explore the large datasets generated. In order to discover digital biomarkers for the study endpoints a case-control study design will be used to compare data patterns from patients with sepsis (cases) and those without sepsis (controls).
CONDITIONS
Official Title
Personalized Swiss Sepsis Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients admitted to an ICU at a Swiss University Hospital
- Patients expected to stay at least 24 hours in the ICU
- Cases: Patients with sepsis 3.0 criteria at ICU admission or who develop sepsis during ICU stay
- Controls: Patients not meeting sepsis criteria during ICU stay
You will not qualify if you...
- Declined general consent or any refusal to use data for research
- Patients with a planned elective stay in the ICU
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 16 locations
1
Clinical Microbiology, University Hospital Basel
Basel, Switzerland, 4031
Actively Recruiting
2
Infectious Diseases and Hospital Epidemiology, University Hospital Basel
Basel, Switzerland, 4031
Actively Recruiting
3
Medical Intensive Care Unit; University Hospital Basel
Basel, Switzerland, 4031
Actively Recruiting
4
Surgical Intensive Care Unit, University Hospital Basel
Basel, Switzerland, 4031
Actively Recruiting
5
Institute for Infectious Diseases, University of Bern
Bern, Switzerland, 3001
Actively Recruiting
6
Division Infectious Diseases, University Hospital Bern
Bern, Switzerland, 3010
Actively Recruiting
7
Intensive Care Medicine, University Hospital Bern
Bern, Switzerland, 3010
Actively Recruiting
8
Division Bacteriology Laboratory, University Hospital Geneva
Geneva, Switzerland, 1205
Actively Recruiting
9
Division Infectious Diseases, University Hospital Geneva
Geneva, Switzerland, 1205
Actively Recruiting
10
Intensive Care Medicine, University Hospital Geneva
Geneva, Switzerland, 1205
Actively Recruiting
11
Division Intensive Care Medicine, University Hospital Lausanne
Lausanne, Switzerland, 1011
Actively Recruiting
12
Institute of Microbiology, University Hospital Lausanne
Lausanne, Switzerland, 1011
Actively Recruiting
13
Service Infectious Diseases, University Hospital Lausanne
Lausanne, Switzerland, 1011
Actively Recruiting
14
Institute for Medical Microbiology, University Hospital Zurich
Zurich, Switzerland, 8006
Not Yet Recruiting
15
Division Infectious Diseases, University Hospital Zurich
Zurich, Switzerland, 8091
Not Yet Recruiting
16
Institute for Intensive Medicine, University Hospital Zurich
Zurich, Switzerland, 8091
Not Yet Recruiting
Research Team
A
Adrian Egli, PD Dr.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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