Actively Recruiting
Personalized Theta-burst Stimulation for Long-lasting Changes in Approach/Avoidance Behavior
Led by Northwestern University · Updated on 2025-09-08
26
Participants Needed
1
Research Sites
56 weeks
Total Duration
On this page
Sponsors
N
Northwestern University
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study will assess the long-lasting effects of personalized theta burst stimulation (TBS), a repetitive form of transcranial magnetic stimulation (TMS), over the left prefrontal cortex on the approach/avoidance behavior. TBS will be personalized based on the prefrontal theta rhythm captured with electroencephalography (EEG). The main questions it aims to answer are: 1. does a single session of personalized TBS synchronized with the individual theta rhythm over the left prefrontal cortex results in the outlasting changes in the individual behavior? 2. Does TBS results in the brain rhythms' changes as measured using resting-state EEG?
CONDITIONS
Official Title
Personalized Theta-burst Stimulation for Long-lasting Changes in Approach/Avoidance Behavior
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants must be legal adults between the ages of 18 to 65
- Able and willing to complete study procedures and tasks
You will not qualify if you...
- History or evidence of chronic neurological or mental disorder
- Chronic condition that requires pharmacological treatment over the course of study participation
- Pregnancy or breastfeeding
- History or evidence of alcohol or drug addiction
- Contraindications for transcranial magnetic stimulation (history of seizures, metallic or electric implant in the head/neck area)
- Contraindications for magnetic resonance imaging at 3 Tesla (non-compatible implants, metallic foreign bodies, insulin pump, pacemaker)
AI-Screening
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Trial Site Locations
Total: 1 location
1
Northwestern University Feinberg School of Medicine
Chicago, Illinois, United States, 60611
Actively Recruiting
Research Team
I
Ivan Alekseichuk, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
4
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