Actively Recruiting
Personalized Tobacco Treatment in Primary Care (MOTIVATE)
Led by Washington University School of Medicine · Updated on 2026-02-09
850
Participants Needed
1
Research Sites
261 weeks
Total Duration
On this page
Sponsors
W
Washington University School of Medicine
Lead Sponsor
N
National Institute on Drug Abuse (NIDA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study examines the application of precision treatment intervention for smoking cessation from both the clinician perspective and patient perspective, and compares it to usual care on tobacco treatment in the primary care setting. The precision treatment intervention includes personalized tobacco treatment recommendations using the patient's clinical, genetic, and biomarker information. This approach may increase effectiveness and adherence for the patient, and increase the clinician's likelihood of prescribing.
CONDITIONS
Official Title
Personalized Tobacco Treatment in Primary Care (MOTIVATE)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient at participating clinic
- Age 18 years or older
- Current smoker of at least 5 cigarettes per day
- Can speak and understand English
- Willing to consider medication to help reduce craving or smoking such as nicotine patch, lozenge, or varenicline
You will not qualify if you...
- Active use of smoking cessation medication within the past 30 days
- Receipt of smoking cessation medication or prescription within the past 30 days
- Contraindications for combination nicotine replacement therapy or varenicline, including allergic reactions, current cardiac problems, or pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Washington University School of Medicine
St Louis, Missouri, United States, 63110
Actively Recruiting
Research Team
L
Li-Shiun Chen, ScD, MD, MPH
CONTACT
A
Alex Ramsey, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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