Actively Recruiting
Personalized Transcranial Direct Current Stimulation in Stroke Recovery
Led by The Methodist Hospital Research Institute · Updated on 2026-03-02
80
Participants Needed
1
Research Sites
142 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The central objective of this application is to explore the neural substrate of personalized tDCS (ptDCS) and to determine whether the paradigm for each stroke patient can predict the amount of sustained clinical improvement through increased connectivity as measured by a biomarker of plasticity.
CONDITIONS
Official Title
Personalized Transcranial Direct Current Stimulation in Stroke Recovery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Symptomatic ischemic or hemorrhagic stroke confirmed by CT or MRI causing hemiparesis (muscle strength 1-4)
- Age over 18 years, any gender, all racial and ethnic groups
- Stroke occurred more than 3 months ago
- Modified Ashworth Scale score less than 3 in the affected upper limb
- Passive range of motion in shoulder, elbow, wrist, and hand within functional limits
- Able to follow two-step commands
You will not qualify if you...
- History of severe alcohol or drug abuse, severe psychiatric illness, poor motivation, or serious cognitive or language impairments
- Bilateral weakness or sensory loss due to peripheral nerve, muscle, or orthopedic injury
- Severe uncontrolled medical conditions including cardiovascular disease, rheumatoid arthritis, active cancer, renal disease, end-stage pulmonary or cardiovascular disease, epilepsy, or other deteriorated conditions
- Unstable cardiac arrhythmia
- Pregnancy
- Metallic implants in the head, pacemakers, or prior brain surgeries that prevent safe stimulation
- History of seizures
- Non-English speakers without access to a translator for all study sessions
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Houston Methodist Hospital
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
N
Neha Sudarshan, MD
CONTACT
T
Timea Hodics, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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