Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT06395649

Personalized Treatment by rTMS in Chronic Pain

Led by Aalborg University · Updated on 2026-05-12

90

Participants Needed

1

Research Sites

241 weeks

Total Duration

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AI-Summary

What this Trial Is About

Previous research has shown the effectiveness of magnetic stimulation of the brain as a supplemental treatment for various conditions, such as depression and chronic pain. However, the application of magnetic stimulation has been standardized across patients without considering individual differences. This one-size-fits-all approach results in only half of the patients benefiting from the treatment, with the other half seeing no improvement in their symptoms. Therefore, a study on individuals with chronic pain will be performed to explore how magnetic stimulation treatments can be tailored to each person. This will involve analyzing brain signal measurements before the start of the therapy and adjusting/personalizing the magnetic stimulations to each individual person.

CONDITIONS

Official Title

Personalized Treatment by rTMS in Chronic Pain

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Presence of chronic pain most days for more than 3 months
  • Average pain intensity between 3 and 9 on a 0 to 10 scale
  • Ability to speak and understand English or Danish
Not Eligible

You will not qualify if you...

  • Pregnant or breastfeeding
  • Current uncontrolled major depression as the main diagnosis
  • Current history of substance abuse
  • Inability to cooperate, understand the protocol, or complete questionnaires
  • Contraindications to TMS (e.g., epilepsy, cranial implanted ferromagnetic devices, facial metal tattoos or permanent makeup)
  • Unable to complete the Transcranial Magnetic Stimulation Adult Safety Screen questionnaire
  • Participation in other research studies within 1 month before inclusion

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Aalborg University

Gistrup, North Denmark, Denmark, 9260

Actively Recruiting

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Research Team

E

Enrico De Martino, Dr

CONTACT

D

Daniel Ciampi de Andrade, Prof

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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