Actively Recruiting

Age: 18Years +
All Genders
NCT06635564

Personalized ViscoElastic Testing-guided Bleeding Management In Liver Surgery, Neurosurgery and Obstetrics

Led by Medical University of Vienna · Updated on 2025-05-23

240

Participants Needed

1

Research Sites

108 weeks

Total Duration

On this page

Sponsors

M

Medical University of Vienna

Lead Sponsor

S

Synapse - Research Institute Maastricht

Collaborating Sponsor

AI-Summary

What this Trial Is About

The ClotPro analyzer is a new generation viscoelastic analyzer for the in vitro assessment of blood coagulation. This study aims to assess the agreement of ClotPro 6.0, ROTEM delta, and TEG 6s in three distinct cohorts: i) patients with liver disease undergoing liver surgery, ii) pregnant women undergoing elective cesarean section, and iii) patients undergoing elective intracranial neurosurgery. Further coagulation tests will be performed (standard laboratory coagulation tests, thrombin and plasmin generation tests) in an exploratory fashion to compare them with viscoelastic test results. The obtained test results will not result in any diagnostic or therapeutic consequences for patients included in this study.

CONDITIONS

Official Title

Personalized ViscoElastic Testing-guided Bleeding Management In Liver Surgery, Neurosurgery and Obstetrics

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients undergoing elective liver surgery, including liver resection (segmental, right or left hepatectomy, extended hepatectomy) or orthotopic liver transplantation
  • Pregnant women scheduled for an elective caesarean section
  • Patients undergoing elective intracranial neurosurgery
  • Written informed consent provided
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

Medical University of Vienna

Vienna, Austria, Austria, 1090

Actively Recruiting

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Research Team

N

Nikolaus Hofmann, MD

CONTACT

C

Carlo Martin, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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