Actively Recruiting
Persuasive Health Communication Intervention for HIV/HCV
Led by University of South Florida · Updated on 2026-04-08
2000
Participants Needed
1
Research Sites
138 weeks
Total Duration
On this page
Sponsors
U
University of South Florida
Lead Sponsor
N
National Institute on Drug Abuse (NIDA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
A major impediment to emergency department (ED)-based HIV/HCV screening success is that often ED patients at risk for, or later diagnosed with, HIV and HCV decline testing. In this R01 project, the research team will assess how well a promising, easy-to-use, one-time, minimal-training-needed, very brief persuasive health communication intervention (PHCI) increases acceptance of testing among adult ED patients who either currently, formerly or never injected drugs and initially declined HIV/HCV screening. The research team will conduct a randomized, controlled trial (RCT) at EDs within the Mount Sinai Health System to compare the efficacy of the PHCI when delivered by a video vs. an HIV/HCV counselor. Patients who initially declined HIV/HCV screening will be stratified by injection-drug use (IDU) history cohorts: (1) current/former PWIDs, (2) never/non-PWIDs. Within each IDU history cohort, the research team will randomly assign participants (1:1:1) to a PHCI delivered by: (1) a video with captions, (2) a video without captions, (3) an HIV/HCV counselor. This R01 project will be conducted at Mount Sinai affiliate hospitals EDs. For Aim 2, the research team will determine if screening acceptance is similar across IDU history cohorts. For Aim 3, the research team will further compare the two delivery forms of the PHCI through a health economics assessment, both independent of IDU history and within each IDU history cohort.
CONDITIONS
Official Title
Persuasive Health Communication Intervention for HIV/HCV
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years old or older
- Speak English or Spanish and able to provide informed consent
- Not infected with HIV or HCV (per medical records and patient report)
- Not currently participating in any HIV or HCV research studies
- Not tested for HIV or HCV within the past 12 months (per medical records and patient report)
You will not qualify if you...
- Younger than 18 years old
- Unable to speak English or Spanish
- Tested positive for HIV or HCV
- Currently enrolled in another HIV or HCV research study
- Tested for HIV or HCV in the past 12 months
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Icahn School of Medicine at Mount Sinai
New York, New York, United States, 10128
Actively Recruiting
Research Team
R
Roland C Merchant, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
3
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