Actively Recruiting
PETAL Trial: Impact of Gallium-68 Pentixafor PET-CT on Surgical Outcomes in Primary Aldosteronism
Led by Seoul National University Hospital · Updated on 2025-06-18
90
Participants Needed
2
Research Sites
127 weeks
Total Duration
On this page
Sponsors
S
Seoul National University Hospital
Lead Sponsor
S
Samsung Medical Center
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study is a randomized controlled trial to assess the clinical utility of gallium-68 pentixafor PET/CT in the management of primary aldosteronism (PA). We aim to evaluate whether the addition of 68Ga-pentixafor PET/CT to standard adrenal venous sampling (AVS) improves surgical outcomes in patients with unilateral PA.
CONDITIONS
Official Title
PETAL Trial: Impact of Gallium-68 Pentixafor PET-CT on Surgical Outcomes in Primary Aldosteronism
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 19 years or older
- Diagnosed with primary aldosteronism according to 2016 Endocrine Society guidelines
- Completed adrenal CT scan
- Provided signed informed consent
You will not qualify if you...
- Women who are pregnant, breastfeeding, or may become pregnant
- Refusal to undergo surgery
- Unable or unwilling to undergo 68Ga-Pentixafor PET/CT, 11C-Metomidate PET/CT, or adrenal venous sampling due to underlying conditions
- Refusal or adverse reactions to dexamethasone premedication required for 11C-Metomidate PET/CT
- History of abdominal open surgery or retroperitoneal surgery on the planned adrenalectomy side
- Deemed unsuitable for the study by the investigator
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Samsung Medical Center
Seoul, Gangnam-gu, South Korea, 06351
Actively Recruiting
2
Seoul National University Hospital
Seoul, Jongno-gu, South Korea, 03080
Actively Recruiting
Research Team
S
Seungho Lee, M.D
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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