Actively Recruiting
PET/CT GUIDED BIOPSY VERSUS CT GUIDED BIOPSY IN EVALUATION OF SUSPECTED LUNG NEOPLASMS
Led by All India Institute of Medical Sciences, Bhubaneswar · Updated on 2025-04-11
108
Participants Needed
1
Research Sites
126 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Percutaneous CT guided biopsy is a well-established, standard sampling technique for suspected neoplastic lesions located in peripheral region in lung parenchyma. Inconclusive results on CT guided biopsy is substantially higher in large lung lesions which are prone to cause peripheral pneumonia, atelectasis and even regional necrosis, which are hard to be distinguished from tumor on CT images. Functional imaging guided biopsy like PET/CT guided biopsy identifies areas of highest concentration of neoplastic cells and provides accurate results. Only a few studies have been done regarding PET/CT guided biopsy and studies omparing PET/CT guided and CT guided percutaneous transthoracic lung biopsy are very few and this study would be a randomized trial comparing these diagnostic modalities in terms of diagnostic yield, diagnostic accuracy of sample and complications.
CONDITIONS
Official Title
PET/CT GUIDED BIOPSY VERSUS CT GUIDED BIOPSY IN EVALUATION OF SUSPECTED LUNG NEOPLASMS
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age above 18 years
- INR less than 1.2 and platelet counts greater than 80,000/mm3
- Lung lesion larger than 10 mm on CT thorax
- Lesions accessible for CT-guided biopsy
You will not qualify if you...
- Pre-existing bleeding disorders such as hemophilia or coagulopathy defined by INR 1.2 or higher and platelet counts 80,000/mm3 or less
- Refusal to provide consent
- Signs of low blood flow like hypotension or cyanosis
- Hypoxemia with oxygen saturation below 94% measured by pulse oximeter
- Pregnant or lactating females
- Non-cooperative individuals
- Lesions deemed inaccessible based on pre-biopsy planning
- Serum creatinine level above 2 mg/dl
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
All India Institute of Medical Sciences, Bhubaneswar
Bhubaneswar, Odisha, India, 751019
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here