Actively Recruiting
PET/CT Imaging to Evaluate Cardiac Radiation Damage in Patients With Lung or Esophageal Cancer, EUCLID Trial
Led by Thomas Jefferson University · Updated on 2026-02-10
20
Participants Needed
1
Research Sites
284 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This clinical trial examines positron emission tomography (PET)/computed tomography (CT) in evaluating cardiac radiation damage in patients with lung or esophageal cancer. As part of the treatment for lung or esophageal cancer, patients will undergo radiation therapy. Sometimes, during this treatment, the heart is also subjected to some radiation which could affect its function, either increasing or decreasing the function. It is not known the consequences of this change nor is it known if doctors can detect the changes associated with the radiation. Sarcoidosis FDG positron emission tomography (PET)-computed tomography (CT) scans are a common way to image cardiac inflammation and myocardial viability. This study may help doctors image the heart before, during and after radiotherapy to monitor any changes.
CONDITIONS
Official Title
PET/CT Imaging to Evaluate Cardiac Radiation Damage in Patients With Lung or Esophageal Cancer, EUCLID Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed and dated informed consent form provided
- Willing to follow all study procedures and available for entire study duration
- Male or female aged 18 years or older
- Life expectancy of at least 3 months as assessed by Radiation Oncologist
- Mean heart radiation dose expected to be 5 Gy or greater
- Pathologically confirmed lung or esophageal cancer
- Planned radiation treatment course for lung or esophageal cancer, including both standard and hypofractionation schedules
You will not qualify if you...
- Contraindication to FDG PET-CT scans as determined by radiation oncologist or nuclear medicine radiologist
- Receiving palliative radiation doses defined as 20 Gy in 5 fractions
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, United States, 19107
Actively Recruiting
Research Team
Y
Yevgeniy Vinogradskiy, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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