Actively Recruiting
PET/MRI/EEG Imaging Study in Epilepsy
Led by Massachusetts General Hospital · Updated on 2026-04-23
30
Participants Needed
1
Research Sites
171 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to better understand how epilepsy alters brain function through neuroimaging of healthy people and people with epilepsy. The study investigates how changes in brain metabolism (sugar consumption, measured by positron emission tomography \[FDG-PET\], and blood flow, measured by functional magnetic resonance imaging \[fMRI\]) relate to abnormal interictal electrical activity associated with epilepsy (measured by electroencephalography \[EEG\]). The study will also compare how the three imaging modalities localize regions of abnormal function in the brain.
CONDITIONS
Official Title
PET/MRI/EEG Imaging Study in Epilepsy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 or older
- Diagnosed with epilepsy with abnormal interictal EEG (for subjects with epilepsy)
You will not qualify if you...
- Contraindications to PET, MRI, or EEG imaging
- History of severe brain disease such as stroke and head trauma
- History of brain surgery
- History of type I or II diabetes mellitus
- Fasting plasma glucose level >200 mg/dL
- Employed under direct supervision of the PI conducting the research
- Current use of drugs that modulate brain function (for healthy subjects)
- Current or past history of major medical, neurological, or psychiatric conditions (for healthy subjects)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Athinoula A. Martinos Center
Charlestown, Massachusetts, United States, 02129
Actively Recruiting
Research Team
M
Magdelena S Allen, BA
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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