Actively Recruiting
PH-DyPred: A Multimodal Dynamic Risk Prediction Study in Pulmonary Hypertension
Led by First Affiliated Hospital of Fujian Medical University · Updated on 2025-08-28
1000
Participants Needed
1
Research Sites
209 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Pulmonary hypertension (PH) is a progressive cardiopulmonary disease characterized by elevated pulmonary artery pressure and vascular remodeling, which leads to right heart failure and increased mortality. Despite advances in diagnostics, risk stratification remains limited due to the disease's heterogeneity. This study aims to develop and validate a dynamic risk prediction model for PH by integrating multimodal data-including echocardiography, Cardiac MRI, PET-MR, ECG, biomarkers, and clinical features-using advanced machine learning algorithms. The study will establish a prospective cohort of PH patients to explore predictive markers, stratify prognosis, and provide a scientific basis for early warning and individualized management.
CONDITIONS
Official Title
PH-DyPred: A Multimodal Dynamic Risk Prediction Study in Pulmonary Hypertension
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older
- Pulmonary artery systolic pressure (PASP) 6535 mmHg as estimated by echocardiography
- Provided written informed consent
You will not qualify if you...
- Severe hepatic or renal insufficiency
- Malignancy under active treatment
- Severe infection
- Active autoimmune disease
- Major surgery within the past 3 months
- Pregnant or breastfeeding women
- Severe psychiatric disorder impairing ability to comply with the study protocol
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital of Fujian Medical University
Fuzhou, Fujian, China, 350011
Actively Recruiting
Research Team
D
Dajun Chai, MD
CONTACT
B
Biyun Chen, MSc
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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