Actively Recruiting

Phase 2
Age: 18Years +
All Genders
Healthy Volunteers
NCT05181891

Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking

Led by Washington State University · Updated on 2024-06-25

205

Participants Needed

1

Research Sites

198 weeks

Total Duration

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AI-Summary

What this Trial Is About

Using a randomized controlled trial (RCT), the goal of this study is to evaluate the ability of evidence based behavioral treatment (contingency management: CM) to significantly decrease alcohol use and cigarette smoking among treatment-seeking smokers with an alcohol use disorder (AUD) who have initiated pharmacotherapy (varenicline; VC) for smoking cessation.

CONDITIONS

Official Title

Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • 4 or more standard drinks on the same occasion for women (5 or more for men) on at least 4 occasions in the prior 30 days
  • Seeking treatment for alcohol use disorder
  • Seeking treatment for smoking cessation
  • Aged 18 years or older
  • Diagnosed with alcohol use disorder according to DSM-5
  • Currently smoking daily (100 or more lifetime cigarettes plus current daily smoking)
  • Able to read and speak English
  • Able to provide written informed consent
  • Breath alcohol level of 0.00 during informed consent
  • At least one EtG-positive urine test and one COT-positive urine test during the induction period
  • Attended at least 4 of 6 possible visits during the induction period
Not Eligible

You will not qualify if you...

  • History of alcohol detoxification or seizures in the last 12 months indicating risk of dangerous withdrawal or participant concern about withdrawal
  • Currently receiving any pharmacotherapy for alcohol
  • Currently receiving any pharmacotherapy for smoking
  • Any suicide attempt in the last 20 years
  • Any medical or psychiatric condition that would compromise safe participation as determined by study doctors

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Washington State University

Spokane, Washington, United States, 99202

Actively Recruiting

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Research Team

A

Abigail Bowen, MS

CONTACT

S

Sterling McPherson, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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