Actively Recruiting
Pharmacogenetic Testing of Patients With Unwanted Adverse Drug Reactions or Therapy Failure
Led by University Hospital, Basel, Switzerland · Updated on 2025-05-14
400
Participants Needed
1
Research Sites
354 weeks
Total Duration
On this page
Sponsors
U
University Hospital, Basel, Switzerland
Lead Sponsor
T
Toppharm Apotheke Hersberger, Spalenberg 41, CH-4051 Basel
Collaborating Sponsor
AI-Summary
What this Trial Is About
Genetic makeup of a patient influences the efficacy and safety profile of a drug. This study is to summarize individual cases, where Pharmacogenetics (PGx) has been applied during pharmaceutical care. The primary objective is the compilation of case reports, where pharmacogenetic testing is applied to determine the hereditable component of the patient's susceptibility to experience therapy failure and/or adverse drug reactions. The experience with the compiled cases will be basis for the development of a reliable standard of procedure for pharmacogenetic testing in the community pharmacy. The cases will be supplemented with information on additional Parameters reported in the literature to affect efficacy or safety of the respective drug.
CONDITIONS
Official Title
Pharmacogenetic Testing of Patients With Unwanted Adverse Drug Reactions or Therapy Failure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- New medication with known pharmacogenetic association (preemptive)
- Current medication with observed adverse drug reactions likely linked to drugs with known pharmacogenetic association (reactive)
- Current medication with observed therapy failure likely linked to drugs with known pharmacogenetic association (reactive)
- Current or new medication and a family history of adverse drug reactions or therapy failure likely linked to drugs with known pharmacogenetic association
- Signed informed consent; if patient is under 14 years old, legal representative must sign informed consent
You will not qualify if you...
- Insufficient knowledge of German language
- Unable to personally visit the study pharmacy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Department of Pharmaceutical Sciences, University Basel
Basel, Switzerland, 4056
Actively Recruiting
Research Team
S
Samuel Allemann, Prof. Dr.
CONTACT
K
Kurt Hersberger, Prof. Dr.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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