Actively Recruiting
Pharmacogenetics of Antidepressant-Induced Disinhibition
Led by University of Calgary · Updated on 2026-05-14
120
Participants Needed
1
Research Sites
417 weeks
Total Duration
On this page
Sponsors
U
University of Calgary
Lead Sponsor
H
Hotchkiss Brain Institute, University of Calgary
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to identify pharmacogenetic profiles associated with selective serotonin reuptake inhibitors (SSRI)-induced behavioral disinhibition in children with Major depressive disorder (MDD), anxiety disorders and/or obsessive-compulsive disorder (OCD) that could be used clinically to reduce the incidence of this adverse event and improve health outcomes.
CONDITIONS
Official Title
Pharmacogenetics of Antidepressant-Induced Disinhibition
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 6 to 24 years
- Medical records are available
- Diagnosis of major depressive disorder, anxiety disorder, or obsessive-compulsive disorder
- Current or past history of SSRI therapy
You will not qualify if you...
- Parent or legal guardian unable to give informed consent
- Child unable to give informed assent
- Unwillingness of child to provide saliva sample for genetic analysis
- Current, past, or suspected diagnosis of attention deficit hyperactivity disorder, oppositional defiant disorder, conduct disorder, bipolar disorder, psychotic disorder, or pervasive developmental disorder
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Child and Adolescent Addiction, Mental Health & Psychiatry
Calgary, Alberta, Canada
Actively Recruiting
Research Team
M
Madison Heintz, MSW
CONTACT
A
Abdullah Al Maruf, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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