Actively Recruiting
Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy
Led by Children's Mercy Hospital Kansas City · Updated on 2025-07-18
40
Participants Needed
1
Research Sites
271 weeks
Total Duration
On this page
Sponsors
C
Children's Mercy Hospital Kansas City
Lead Sponsor
U
University of Kansas Medical Center
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study looks at how a medicine called trihexyphenidyl works in children with dystonic cerebral palsy. The study aims to understand how trihexyphenidyl is broken down and used in the body of pediatric patients and whether this is impacted by a person's genetics. Information from this study will also be used to design future clinical trials.
CONDITIONS
Official Title
Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ages 5 to 17 years
- Diagnosis of cerebral palsy with dystonia causing interference
- Parent or legal guardian of the child with cerebral palsy and dystonia
- Parent or legal guardian willing and able to provide informed permission or assent for the study
You will not qualify if you...
- Currently or previously taking trihexyphenidyl
- Turning 18 years old within the 16-week study period
- Language barrier preventing communication or completing study requirements
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Children's Mercy Hospital Kansas City
Kansas City, Missouri, United States, 64108
Actively Recruiting
Research Team
R
Rose Gelineau-Morel, MD
CONTACT
R
Rachel Nass
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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