Actively Recruiting

All Genders
NCT03511118

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

Led by Duke University · Updated on 2026-04-24

1600

Participants Needed

22

Research Sites

512 weeks

Total Duration

On this page

Sponsors

D

Duke University

Lead Sponsor

T

The Emmes Company, LLC

Collaborating Sponsor

AI-Summary

What this Trial Is About

Over half of women in the US who are breastfeeding their infants take prescription drugs. You are being asked to participate in this study because you are breastfeeding your infant and are currently taking, as part of your medical care, at least one of the drugs we are studying. We are interested in studying drugs commonly prescribed to women who are breastfeeding so we can learn more about the amount of drug that is transferred to breastmilk and estimate how much of drug that is consumed by breastfed infants.

CONDITIONS

Official Title

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Lactating women who are 180 days postpartum or less and are receiving at least one drug of interest as part of standard care
  • Infants who are 180 days old or younger and receive breastmilk from their mother
  • Informed consent and HIPAA authorization obtained according to local guidelines
  • Lactating women who are not legal adults and their infants may participate if assent and guardian consent are obtained per local rules
Not Eligible

You will not qualify if you...

  • Any medical condition that would prevent participation as determined by the patient's physician or the study's principal investigator
  • Known pregnancy during pharmacokinetic sampling

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 22 locations

1

University of California-San Diego Medical Center

La Jolla, California, United States, 92093

Actively Recruiting

2

Loma Linda University Health

Loma Linda, California, United States, 92354

Actively Recruiting

3

Northwestern University

Chicago, Illinois, United States, 60611

Completed

4

Ann and Robert H. Lurie Childrens Hospital of Chicago

Chicago, Illinois, United States, 60614

Actively Recruiting

5

Indiana University Health

Indianapolis, Indiana, United States, 46202

Completed

6

University of Iowa Hospitals and Clinics

Iowa City, Iowa, United States, 52242

Active, Not Recruiting

7

Children's Hospital and Clinics - Minneapolis

Minneapolis, Minnesota, United States, 55404

Actively Recruiting

8

University of New Mexico, Health Sciences Center

Albuquerque, New Mexico, United States, 87131

Completed

9

University of North Carolina Hospital

Chapel Hill, North Carolina, United States, 27599

Completed

10

Duke University Maternal and Fetal Medicine

Durham, North Carolina, United States, 27705

Actively Recruiting

11

Oregon Health & Science University

Portland, Oregon, United States, 97239

Actively Recruiting

12

Hospital of the University of Pennsylvania Department of Maternal Fetal Medicine

Philadelphia, Pennsylvania, United States, 19104

Completed

13

University of Pittsburgh School of Medicine

Pittsburgh, Pennsylvania, United States, 15213

Actively Recruiting

14

Texas Tech University Health Sciences Center School of Medicine.

Amarillo, Texas, United States, 79106

Actively Recruiting

15

University of Texas Medical Branch - Galveston

Galveston, Texas, United States, 77555

Actively Recruiting

16

University of Texas Health Science Center at Houston

Houston, Texas, United States, 77030

Actively Recruiting

17

The Women's Hospital of Texas

Houston, Texas, United States, 77054

Actively Recruiting

18

University of Texas Health Science Center

San Antonio, Texas, United States, 78229

Actively Recruiting

19

University of Utah

Salt Lake City, Utah, United States, 84132

Actively Recruiting

20

University of Washington

Seattle, Washington, United States, 98195-7630

Completed

21

Lawson Health Research Institute

London, Ontario, Canada, N6A 5W9

Completed

22

Centre Hospitalier Universitaire Sainte-Justine

Montreal, Quebec, Canada, H3T IC5

Completed

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Research Team

E

Emily Forgey

CONTACT

C

Cheryl Alderman

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

38

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