Actively Recruiting
Pharmacological and Non-pharmacological Treatment Effects on Children With Different Predicted Myopia Progression Rate
Led by The Hong Kong Polytechnic University · Updated on 2025-09-17
80
Participants Needed
1
Research Sites
152 weeks
Total Duration
On this page
Sponsors
T
The Hong Kong Polytechnic University
Lead Sponsor
T
The University of Hong Kong
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to compare pharmacological and non-pharmacological treatment effects on the children with different predicted myopia progression rate measured by modified multifocal electroretinogram. The main questions it aims to answer are: * the effectiveness of using 0.05% atropine and prescribing DIMS lens for myopia control in children with different myopia progression rates * the contribution of L/M cones in juvenile myopia progression and changes of retinal activities under atropine and DIMS treatment. Participants will have baseline and follow-up eye examinations and given either pharmacological treatment with 0.05% atropine or non-pharmacological treatment with DIMS lens for myopia control. Researchers will compare the changes of refractive errors and axial length after different types of interventions and investigate the relations between the parameters of mfERG responses and the thicknesses of retinal layers and choroid.
CONDITIONS
Official Title
Pharmacological and Non-pharmacological Treatment Effects on Children With Different Predicted Myopia Progression Rate
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be aged between 7 and 9 years
- No reported eye disorder and no family history of eye disease
- Able to participate in the study for 24 months
- No current or past epilepsy
- No current or past asthma
- Have refractive error between -0.50 D and -4.00 D with less than 1.50 D astigmatism
- Best corrected visual acuity of LogMAR 0.0 or better
- No detected eye diseases or disorders after eye exam except myopia
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
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Trial Site Locations
Total: 1 location
1
School of Optometry, Hong Kong Polytechnic University
Hong Kong, Hong Kong, 00000
Actively Recruiting
Research Team
H
Henry HL CHAN, PhD
CONTACT
K
Kaiyip CHOI, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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