Actively Recruiting
Pharyngeal Exercise (Plus Protein)
Led by NYU Langone Health · Updated on 2025-08-05
120
Participants Needed
2
Research Sites
240 weeks
Total Duration
On this page
Sponsors
N
NYU Langone Health
Lead Sponsor
N
National Institute on Aging (NIA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The swallowing muscles are prone to decreased strength and function as part of the natural aging process which can lead to difficulty swallowing, malnutrition, and frailty. Exercise and nutrition are powerful stimulators of muscular change. The proposed research will investigate the effectiveness of a 12-week proactive regimen of swallowing exercises (with or without daily protein supplement drinks) to improve the composition, force, and physiology of the swallowing muscles and explore the relationship to overall health and physical function in 80 community-dwelling older adults. Each participant will serve as their own control for 12 weeks before being randomized to complete swallowing exercises alone or swallowing exercises with protein drinks.
CONDITIONS
Official Title
Pharyngeal Exercise (Plus Protein)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants must be 65 years of age or older
- Participants must score a 1 or 2 on the FRAIL scale or 4 or greater on the SARC-F Questionnaire
- Participants must score 26 or greater on the Montreal Cognitive Assessment (MoCA)
- Willingness to participate in the study procedures
You will not qualify if you...
- Known structural or neurological causes of dysphagia
- Unable to consume high levels of protein due to Chronic Kidney Disease Stage 3 or higher
- Contraindications to 3T whole body MRI scanners such as pacemaker, cerebral aneurysm clip, cochlear implant, shrapnel in critical areas, metal in the eye, or claustrophobia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
NYU Steinhardt School of Education
New York, New York, United States, 10003
Actively Recruiting
2
NYU Langone Health
New York, New York, United States, 10017
Actively Recruiting
Research Team
S
Sonja Molfenter
CONTACT
M
Maria Travino Sampler
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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