Actively Recruiting

Phase 2
Age: 6Years +
All Genders
NCT07552077

A Phase 2, Baseline-Controlled Study Evaluating the Safety and Efficacy of PTX-022 (Sirolimus) Topical Gel 3.9% in the Treatment of Angiokeratomas (LOTU)

Led by Palvella Therapeutics, Inc. · Updated on 2026-04-27

15

Participants Needed

4

Research Sites

74 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to evaluate the safety and effectiveness of the experimental drug PTX-022 in the treatment of angiokeratomas

CONDITIONS

Official Title

A Phase 2, Baseline-Controlled Study Evaluating the Safety and Efficacy of PTX-022 (Sirolimus) Topical Gel 3.9% in the Treatment of Angiokeratomas (LOTU)

Who Can Participate

Age: 6Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants must be 6 years or older
  • Diagnosed with angiokeratoma
  • Able and willing to comply with all protocol-related activities
  • Willing and able to provide written informed consent
Not Eligible

You will not qualify if you...

  • Any significant concurrent condition that could adversely affect participation
  • Any history of allergy or hypersensitivity to sirolimus, sirolimus-like medications, or PTX-022
  • Patients deemed unwilling or unable to remain compliant with all tests, procedures, and study drug administration

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

Unified Health

Sherman Oaks, California, United States, 91403

Not Yet Recruiting

2

Cleaver Medical Group

Dawsonville, Georgia, United States, 30534

Actively Recruiting

3

Vividia Dermatology

Las Vegas, Nevada, United States, 89148

Not Yet Recruiting

4

Epiphany Dermatology

Southlake, Texas, United States, 76092

Actively Recruiting

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Research Team

E

Emily Cook

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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