Actively Recruiting

Phase 1
Age: 18Years - 75Years
All Genders
NCT06944444

A Phase I Clinical Study of SSS59 Monotherapy in Patients With Advanced Malignant Tumors

Led by Shenyang Sunshine Pharmaceutical Co., LTD. · Updated on 2025-04-29

154

Participants Needed

1

Research Sites

139 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study was an open-label phase I study to evaluate the safety, pharmacokinetics, and antitumor activity of SSS59 as a single agent in patients with advanced malignancies.

CONDITIONS

Official Title

A Phase I Clinical Study of SSS59 Monotherapy in Patients With Advanced Malignant Tumors

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically and/or cytologically documented locally advanced, recurrent, or metastatic malignancies
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0-1
  • Expected survival of more than 3 months
  • Signed informed consent form
  • Adequate organ function
Not Eligible

You will not qualify if you...

  • Any remaining adverse events greater than grade 1 from prior anti-tumor treatment, except hair loss and fatigue
  • Pregnant or nursing women, or men and women who are ready to have children
  • Symptomatic central nervous system metastasis
  • Allergy to other antibody drugs or any excipients in the study drug
  • Major surgery within 4 weeks before first dose
  • Participation in another clinical study unless observational or follow-up

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Shanghai First People's Hospital

Shanghai, Shanghai Municipality, China

Actively Recruiting

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Research Team

Q

Qi Li, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

4

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