Actively Recruiting
A Phase II Clinical Study of Epigallocatechin-3-gallate in Patients With Esophageal Squamous Cancer
Led by Shandong Cancer Hospital and Institute · Updated on 2024-05-03
72
Participants Needed
1
Research Sites
108 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The investigators conduct this phase II study to evaluate safety and effectiveness of EGCG in patients with dysphagia. Swallowing-related dysphagia and pain scores were recorded using the numerical rating scale (NRS) daily . Barium meal radiography was utilized to measure the luminal size and the length of the lesion area both before and after a week of EGCG treatment. The scales are translated into Chinese and guides in Chinese are developed instructing how to use the scales and perform the assessments.
CONDITIONS
Official Title
A Phase II Clinical Study of Epigallocatechin-3-gallate in Patients With Esophageal Squamous Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Confirmed pathological esophageal squamous cell carcinoma
- 18 years old or older
- Eastern Cooperative Oncology Group Performance Status (ECOG PS) of 0 or 1
- No previous anti-tumor treatment
- No esophageal bleeding or fistula
- Adequate hemocyte count and normal liver and kidney function
- Esophageal obstruction classified as grade 2 or grade 3 by Stooler's dysphagia score
You will not qualify if you...
- Pregnant or breastfeeding women
- Known allergy or hypersensitivity to any kind of green tea extract
- Placement of small intestinal feeding tube or previous endoscopic stent treatment
- Unable or unwilling to take oral liquids
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shandong Cancer Hospital
Jinan, Shandong, China, 250117
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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