Actively Recruiting
Phase II Cohort of Spinal Stereotactic Radiotherapy in Patients Using a MR LINAC
Led by M.D. Anderson Cancer Center · Updated on 2026-01-14
40
Participants Needed
1
Research Sites
142 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To learn whether giving spinal stereotactic radiosurgery (SRSS) that uses a more advanced imaging scan method called Magnetic Resonance imaging with a Linear Accelerator (MR-LINAC) during treatment will lead to improved responses to treatment and better quality of life. SRSS is radiation therapy given to the area around your spine.
CONDITIONS
Official Title
Phase II Cohort of Spinal Stereotactic Radiotherapy in Patients Using a MR LINAC
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Radiographically confirmed spinal disease within 4 weeks of registration
- Eligible for spine stereotactic radiosurgery or stereotactic body radiation therapy as determined by treating physician or spine conference
- Maximum of 3 contiguous vertebral levels involved with spine metastasis to be treated
- Documented diagnosis of cancer
- Motor strength of at least 4 out of 5 in the affected extremity
- Karnofsky Performance Score of 40 or higher or ECOG score of 3 or lower
You will not qualify if you...
- Patients with highly radiosensitive cancers likely to respond to conventional radiation alone (such as lymphoma or multiple myeloma)
- Unable to undergo MRI of the spine with contrast
- Pregnant patients
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
M D Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
D
Debra N. Yeboa, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
2
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