Actively Recruiting
PHASE II EVALUATION OF CYTOREDUCTION SURGERY AND HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY (CRS/HIPEC) IN GASTRIC CANCER
Led by Banner Health · Updated on 2026-05-01
30
Participants Needed
1
Research Sites
514 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a Phase II treatment study analyzing the role of preoperative chemotherapy, preoperative laparoscopic HIPEC, and gastrectomy with CRS/HIPEC in gastric adenocarcinoma patients with cytology-positive only carcinomatosis, radiologically-occult carcinomatosis, or radiology apparent peritoneal-surface only metastatic disease.
CONDITIONS
Official Title
PHASE II EVALUATION OF CYTOREDUCTION SURGERY AND HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY (CRS/HIPEC) IN GASTRIC CANCER
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years and above with no upper age limit
- ECOG performance status of 2 or less
- Cytologic or histologic confirmation of stomach or gastroesophageal junction adenocarcinoma
- Adequate kidney and bone marrow function including leukocytes >= 3,000/uL, neutrophils >= 1,500/uL, platelets >= 60,000/uL, and serum creatinine <= 1.5 mg/dL
- Metastatic disease limited to the peritoneum, confirmed by positive peritoneal cytology only or visible carcinomatosis on laparoscopy or laparotomy
You will not qualify if you...
- Metastatic disease beyond the peritoneum, including to liver, brain, or lungs
- Current infections such as pneumonia or wound infections that prevent treatment
- Pregnant women or women who are breastfeeding and do not agree to use effective contraception
- Unstable angina or New York Heart Association Grade II or higher congestive heart failure
- Inability to comply with study or follow-up procedures
- Known severe allergic reaction to the study chemotherapy requiring hospitalization or causing serious disability
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Banner MD Anderson Cancer Center
Gilbert, Arizona, United States, 85234
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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