Actively Recruiting
A Phase II Trial Evaluating Upfront Stereotactic Body Radiotherapy in Stage III Advanced Non-small Cell Lung Cancer
Led by All India Institute of Medical Sciences · Updated on 2026-05-04
20
Participants Needed
1
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of the study is to test the feasibility \& loco-regional control rate by combining high precision SBRT with chemotherapy in stage III NSCLC in tumor/lymph nodes if tumors/lymph node size with ≤ 6cms in size.
CONDITIONS
Official Title
A Phase II Trial Evaluating Upfront Stereotactic Body Radiotherapy in Stage III Advanced Non-small Cell Lung Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 or above and less than 75 years
- Histologically proven non-small cell lung cancer
- Stage T1-4, N1-3, M0 with maximum tumor size less than 6 cms and 3 or fewer stations of largest lymph node size less than 4 cms
- ECOG status 0-1
- Available to attend long term follow-up
- Written informed consent for treatment
You will not qualify if you...
- Metastatic disease
- Tumor size greater than 6 cm
- Involved lymph node size greater than 4 cms and more than 3 stations of lymph nodes involved
- Presence of superior vena cava obstruction
- Tumor invading or encasing the proximal bronchial tree, esophagus, or pericardium
- Previous radiotherapy to thorax
- Small cell lung cancer histology
- Age less than 18 or greater than 75 years
- Patients on anticoagulant therapy and ultra-central cavitary tumors
- Poor performance status (ECOG 2-3)
- Immunocompromised states
- Viral markers negative
- Pregnant women
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Nci, Aiims-Jhajjar
Jhajjar, Haryana, India, 124105
Actively Recruiting
Research Team
A
Aman Sharma, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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