Actively Recruiting
A Phase IIb Dose-ranging Study to Assess the Efficacy and Safety of GIA632 in Participants With Non-segmental Vitiligo
Led by Novartis Pharmaceuticals · Updated on 2026-05-14
210
Participants Needed
22
Research Sites
205 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main purpose of this multicenter, randomized, double-blind, placebo-controlled Phase 2b study is to investigate the safety and efficacy of GIA632 in participants with NSV and to identify the optimal dose to be promoted into the confirmatory Phase 3 program.
CONDITIONS
Official Title
A Phase IIb Dose-ranging Study to Assess the Efficacy and Safety of GIA632 in Participants With Non-segmental Vitiligo
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed informed consent before participation
- Male or female assigned at birth aged 18 years or older at screening
- Diagnosed with non-segmental vitiligo confirmed by physical exam
- Non-segmental vitiligo covering at least 0.5% of facial body surface area and F-VASI score of 0.5 or more
- Non-segmental vitiligo covering 3% or more of non-facial body surface area (excluding hands and feet) with T-VASI score between 3 and 60
You will not qualify if you...
- Unable or unwilling to follow study procedures or complete questionnaires
- Have segmental or mixed vitiligo or other skin conditions that interfere with assessments
- Previous use of biologic drugs targeting IL-15 or IL-15 receptors
- Prior attempt or completion of depigmentation therapy for non-segmental vitiligo
- Use of prohibited medications or treatments as defined by the study protocol
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 22 locations
1
Cahaba Derm and skin hlth ctr 27
Birmingham, Alabama, United States, 35244
Actively Recruiting
2
Clinical Trials Research Institute
Thousand Oaks, California, United States, 91320
Actively Recruiting
3
Miami Derm and Laser Institute
Miami, Florida, United States, 33173
Actively Recruiting
4
Global Clinical Professionals
St. Petersburg, Florida, United States, 33714
Actively Recruiting
5
Dawes Fretzin Clinical Rea Group
Indianapolis, Indiana, United States, 46256
Actively Recruiting
6
Hamzavi Dermatology
Fort Gratiot, Michigan, United States, 48059
Actively Recruiting
7
Revival Research Institute
Troy, Michigan, United States, 48084
Actively Recruiting
8
Skin Specialists PC
Omaha, Nebraska, United States, 68144
Actively Recruiting
9
Las Vegas Dermatology
Las Vegas, Nevada, United States, 89144
Actively Recruiting
10
Equity Medical
The Bronx, New York, United States, 10455
Actively Recruiting
11
International Clinical Research Tennessee LCC
Murfreesboro, Tennessee, United States, 37130
Actively Recruiting
12
Center for Clinical Studies
Houston, Texas, United States, 77030
Actively Recruiting
13
Austin Inst for Clinical Research
Pflugerville, Texas, United States, 78660
Actively Recruiting
14
Virginia Clinical Research
Norfolk, Virginia, United States, 23507
Actively Recruiting
15
Novartis Investigative Site
Sydney, New South Wales, Australia, 2010
Actively Recruiting
16
Novartis Investigative Site
Waitara, New South Wales, Australia, 2077
Actively Recruiting
17
Novartis Investigative Site
Melbourne, Victoria, Australia, 3000
Actively Recruiting
18
Novartis Investigative Site
Mississauga, Ontario, Canada, L4Y 4C5
Actively Recruiting
19
Novartis Investigative Site
Newmarket, Ontario, Canada, L3Y 5G8
Actively Recruiting
20
Novartis Investigative Site
Toronto, Ontario, Canada, M3H 5Y8
Actively Recruiting
21
Novartis Investigative Site
Québec, Quebec, Canada, G1V 4X7
Actively Recruiting
22
Novartis Investigative Site
Urayasu, Chiba, Japan, 279-0021
Actively Recruiting
Research Team
N
Novartis Pharmaceuticals
CONTACT
N
Novartis Pharmaceuticals
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
5
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