Actively Recruiting
Phase I/II Clinical Study to Evaluate VB15010 Tablets in Patients With Advanced Solid Tumors
Led by Zhejiang Yangli Pharmaceutical Technology Co., Ltd. · Updated on 2025-02-11
188
Participants Needed
1
Research Sites
73 weeks
Total Duration
On this page
Sponsors
Z
Zhejiang Yangli Pharmaceutical Technology Co., Ltd.
Lead Sponsor
S
Shandong Cancer Hospital and Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research is designed to determine if experimental treatment with PARP1 inhibitor, VB15010 is safe, tolerable, and has anti-cancer activity in patients with advanced solid tumors.
CONDITIONS
Official Title
Phase I/II Clinical Study to Evaluate VB15010 Tablets in Patients With Advanced Solid Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older at screening
- Confirmed advanced malignancy by tissue or cell analysis
- Progressive cancer at study entry
- Adequate organ and bone marrow function as defined by the protocol
- Presence of homologous recombination repair gene mutation
You will not qualify if you...
- Major surgery within 4 weeks before first study treatment dose
- Symptomatic or untreated brain metastases or spinal cord compression
- Requirement for continuous corticosteroids over 10mg prednisone or equivalent within 4 weeks before treatment
- Leptomeningeal carcinomatosis
- Diagnosis of myelodysplastic syndrome or acute myeloid leukemia or related features
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Cancer Hospital of Shandong First Medical university
Jinan, Shandong, China, 250000
Actively Recruiting
Research Team
S
Song Jia Project manager, bachelor
CONTACT
Z
Zhang Nan Assistant project manager, bachelor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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