Actively Recruiting
The Phase III Clinical Study of Herombopag for the Treatment of Thrombocytopenia in Chronic Liver Disease Patients Undergoing Elective Invasive Surgery
Led by Jiangsu HengRui Medicine Co., Ltd. · Updated on 2025-11-18
101
Participants Needed
1
Research Sites
69 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study includes Part A and Part B. Part A is a dose-finding study for subjects with chronic liver disease-related thrombocytopenia scheduled for elective surgery. Part B is a multicenter, randomized, double-blind, placebo-controlled Phase III clinical study designed to evaluate the efficacy and safety of Herombopag compared to placebo in patients with chronic liver disease-related thrombocytopenia undergoing elective invasive surgery.
CONDITIONS
Official Title
The Phase III Clinical Study of Herombopag for the Treatment of Thrombocytopenia in Chronic Liver Disease Patients Undergoing Elective Invasive Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female aged 18 years or older with a Child-Pugh score of Class A or Class B
- Platelet count less than 50 x 10^9/L at baseline
- Scheduled for elective invasive procedures or surgeries
You will not qualify if you...
- History of arterial or venous thrombosis, including partial or complete thrombosis
- Evidence of thrombosis in the main portal vein, its branches, or splenic mesenteric system at screening
- Portal vein blood flow velocity less than 10 centimeters/second at screening
- Presence of other diseases that may cause thrombocytopenia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Zhongshan Hospital, affiliated with Fudan University
Shanghai, Shanghai Municipality, China, 200032
Actively Recruiting
Research Team
T
Ting Zhang
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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