Actively Recruiting

Phase 1
Phase 2
Age: 18Years - 80Years
All Genders
NCT05170958

A Phase I/II Clinical Study of LBL-024 in Patients With Advanced Malignant Tumors

Led by Nanjing Leads Biolabs Co.,Ltd · Updated on 2025-05-22

396

Participants Needed

49

Research Sites

255 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To evaluate the phase I/II clinical study of LBL-024 in the treatment of patients with advanced malignant tumors

CONDITIONS

Official Title

A Phase I/II Clinical Study of LBL-024 in Patients With Advanced Malignant Tumors

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Agree to follow the treatment and visit plan and sign the informed consent
  • Aged 18 to 75 years for phase I/IIa, or 18 to 80 years for phase IIb, any gender
  • Adequate organ and bone marrow function confirmed by lab tests
  • Expected survival time of at least 12 weeks
  • ECOG performance status score of 0 or 1
  • Males who can father children and women of childbearing age willing to use effective contraception from consent signing until 6 months after last dose; women must have a negative pregnancy test within 7 days before first dose
Not Eligible

You will not qualify if you...

  • Participation in other unmarketed clinical trials or treatments within 4 weeks before the first dose
  • Brain or meningeal metastases causing clinical symptoms, as judged unsuitable by the investigator
  • History of immunodeficiency, including positive HIV antibody test
  • Pregnant or breastfeeding women
  • Any other conditions deemed by the investigator to affect study compliance or suitability

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 49 locations

1

The First Affiliated Hospital of Anhui Medical University

Hefei, Anhui, China, 230000

Actively Recruiting

2

Anhui Provincial Hospital

Hefei, Anhui, China, 230002

Actively Recruiting

3

The Second Hospital of Anhui Medical University

Hefei, Anhui, China, 230601

Actively Recruiting

4

Peking Union Medical College Hospital

Beijing, Beijing Municipality, China, 100005

Actively Recruiting

5

Cancer Hospital Chinese Academy of Medical Sciences

Beijing, Beijing Municipality, China, 100021

Actively Recruiting

6

Beijing Cancer Hospital

Beijing, Beijing Municipality, China, 100142

Actively Recruiting

7

Chongqing Cancer Hospital

Chongqing, Chongqing Municipality, China, 400030

Actively Recruiting

8

Fujian Cancer Hospital

Fuzhou, Fujian, China, 350000

Actively Recruiting

9

Fujian Medical University Union Hospital

Fuzhou, Fujian, China, 350000

Not Yet Recruiting

10

The First Affiliated Hospital of Xiamen University

Xiamen, Fujian, China, 361000

Actively Recruiting

11

The First Affiliated Hospital,Sun Yat-sen University

Guangzhou, Guangdong, China, 510062

Actively Recruiting

12

Sun Yat-sen University Cancer Center

Guanzhou, Guangdong, China, 510000

Actively Recruiting

13

Guangxi Medical University Cancer Hospital & Guangxi Cancer Institute

Nanning, Guangxi, China, 530000

Actively Recruiting

14

Affiliated Hospital of Zunyi Medical University

Zunyi, Guizhou, China, 563000

Actively Recruiting

15

Sir Run Run Shaw Hospital

Hangzhou, Hangzhou, China, 310000

Actively Recruiting

16

Fourth Hospital of Hebei Medical University

Shijiazhuang, Hebei, China, 050011

Actively Recruiting

17

Harbin Medical University Cancer Hospital

Harbin, Heilongjiang, China, 150000

Actively Recruiting

18

Anyang Tumor Hospital

Anyang, Henan, China, 455000

Actively Recruiting

19

The First Affilated Hospital of Henan University of Science & Technology

Luoyang, Henan, China, 471003

Actively Recruiting

20

Henan Cancer Hospital

Zhengzhou, Henan, China, 450000

Not Yet Recruiting

21

The First Affiliated Hospital of Zhengzhou University

Zhengzhou, Henan, China, 450052

Actively Recruiting

22

Henan Provincial People's Hospital

Zhengzhou, Henan, China

Actively Recruiting

23

Tongji Hospital

Wuhan, Hubei, China, 430000

Actively Recruiting

24

Wuhan Union Hospital of China

Wuhan, Hubei, China, 430000

Actively Recruiting

25

Hubei Cancer Hospital

Wuhan, Hubei, China, 430079

Actively Recruiting

26

Xiangyang Central Hospital

Xiangyang, Hubei, China, 441000

Actively Recruiting

27

Hunan Cancer Hospital

Changsha, Hunan, China, 410031

Actively Recruiting

28

Jiangsu Cancer Hospital

Nanjing, Jiangsu, China, 210000

Actively Recruiting

29

Nanjing First Hospital

Nanjing, Jiangsu, China, 210000

Actively Recruiting

30

Nanjing Drum Tower Hospital

Nanjing, Jiangsu, China, 210008

Actively Recruiting

31

The Second Affiliated Hospital Nanchang University

Nanchang, Jiangxi, China, 330000

Not Yet Recruiting

32

The Ferst Affiliated Hospital of Nanchang University

Nanchang, Jiangxi, China, 330006

Actively Recruiting

33

The First Hospital of Jilin University

Ch’ang-ch’un, Jilin, China, 130000

Actively Recruiting

34

Liaoning Cancer Hospital & Institute

Shenyang, Liaoning, China, 110000

Actively Recruiting

35

The First Hospital of China Medical University

Shenyang, Liaoning, China, 110000

Actively Recruiting

36

Qilu Hospital of Shandong University

Jinan, Shandong, China, 250000

Actively Recruiting

37

Shandong Cancer Hospital & Institute

Jinan, Shandong, China, 250000

Actively Recruiting

38

Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, China, 200032

Actively Recruiting

39

Shanxi Bethune Hospital

Taiyuan, Shanxi, China, 030000

Not Yet Recruiting

40

Shanxi Provincial Cancer Hospital

Taiyuan, Shanxi, China, 030000

Actively Recruiting

41

The First Affiliated Hospital of Xi'An Jiaotong University

Xi’an, Shanxi, China, 710061

Actively Recruiting

42

Sichuan Cancer Hospital

Chengdu, Sichuan, China, 610000

Actively Recruiting

43

Mianyang Central Hospital

Mianyang, Sichuan, China, Mianyang

Not Yet Recruiting

44

Tianjin Medical University Cancer Institute & Hospital

Tianjin, Tianjin Municipality, China, 300181

Actively Recruiting

45

Yunnan Cancer Hospital

Kunming, Yunnan, China, 650000

Actively Recruiting

46

The Second Affiliated Hospital Zhejiang University School of Medicine

Hangzhou, Zhejiang, China, 310000

Actively Recruiting

47

The First Affiliated Hospital Zhejiang University School of Medicine

Hangzhou, Zhejiang, China, 310003

Actively Recruiting

48

Zhejiang Cancer Hospital

Hangzhou, Zhejiang, China, 310005

Actively Recruiting

49

The First Affiliated Hospital of Wenzhou Medical University

Wenzhou, Zhejiang, China, 325015

Actively Recruiting

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Research Team

X

xiangyu ma

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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