Actively Recruiting

Phase 3
Age: 18Years - 80Years
All Genders
NCT06779136

Phase III Clinical Study of MG-K10 Humanized Mab Injection in Subjects With Prurigo Nodularis

Led by Shanghai Mabgeek Biotech.Co.Ltd · Updated on 2025-04-18

160

Participants Needed

1

Research Sites

87 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A phase III clinical study to evaluate the efficacy and safety of a humanized MG-K10 mab injection in subjects with prurigo nodularis.administered every 4 weeks for 56 weeks.

CONDITIONS

Official Title

Phase III Clinical Study of MG-K10 Humanized Mab Injection in Subjects With Prurigo Nodularis

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Voluntarily sign the informed consent form and agree to follow all study visits and procedures
  • Men and women aged 18 to 80 years at the time of informed consent
  • Diagnosed with prurigo nodularis by a dermatologist at screening for at least 3 months
  • Itch severity score (WI-NRS) of 7 or higher in the past 24 hours at screening and an average weekly score of 7 or higher before baseline visit
Not Eligible

You will not qualify if you...

  • Having skin diseases other than prurigo nodularis or mild atopic dermatitis that might affect study results
  • History of moderate to severe atopic dermatitis within 6 months before screening
  • Use of potent or super-potent topical corticosteroids or immunomodulators within 2 weeks before or during screening
  • Evidence of active tuberculosis
  • Participation in another clinical study within 12 weeks or 5 half-lives before screening

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Peking University People's Hospital, Beijing,

Beijing, Bejing, China, 100009

Actively Recruiting

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Research Team

X

xiaofeng xiao Cai, bachelor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Phase III Clinical Study of MG-K10 Humanized Mab Injection in Subjects With Prurigo Nodularis | DecenTrialz