Actively Recruiting
A Phase 1 Study of 177Lu-IM-3050 in Participants With Advanced Cancer
Led by Immunome, Inc. · Updated on 2026-04-06
105
Participants Needed
1
Research Sites
452 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
IM-3050-101 is a Phase 1 study to determine the safety and effectiveness of 177Lu-IM-3050 in treating participants with advanced cancer.
CONDITIONS
Official Title
A Phase 1 Study of 177Lu-IM-3050 in Participants With Advanced Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- Eastern Cooperative Oncology Group performance status (ECOG PS) of 0, 1, or 2
- Histological or cytological diagnosis of a solid tumor
- Participants must be refractory to or have relapsed after at least one prior standard therapeutic regimen
- Participants must be relapsed or refractory to, intolerant of, or not candidates for available therapies with established benefit
- Participants must have measurable disease as per RECIST v.1.1 based on imaging performed during Screening
- Participants must have positive FAP PET/CT uptake during screening
- Participants must have adequate organ function
You will not qualify if you...
- Received certain prior radiation therapy as detailed in the protocol
- Major surgery within 4 weeks or minor surgery within 2 weeks before starting 177Lu-IM-3050
- Known active central nervous system (CNS) primary tumor, metastases, or carcinomatous meningitis
- History of malignant primary brain tumor or other primary solid or hematologic malignancy unless disease-free for at least 3 years
- Recent or ongoing serious infection or other significant medical condition as detailed in the protocol
- Received an investigational product or device within 30 days or 5 half-lives prior to FAP PET/CT imaging tracer or 177Lu-IM-3050
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Excel Diagnostics and Nuclear Oncology Center
Houston, Texas, United States, 77042
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SEQUENTIAL
Primary Purpose
TREATMENT
Number of Arms
1
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