Actively Recruiting
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
Led by Priovant Therapeutics, Inc. · Updated on 2026-04-16
342
Participants Needed
5
Research Sites
175 weeks
Total Duration
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AI-Summary
What this Trial Is About
This study will evaluate the clinical safety and efficacy of oral brepocitinib in participants with lichen planopilaris
CONDITIONS
Official Title
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Scalp biopsy consistent with lichen planopilaris
- Active and symptomatic lichen planopilaris at screening and baseline
- Weight greater than 40 kg and less than 130 kg with body mass index (BMI) of 45 kg/m2 or less
You will not qualify if you...
- History of lymphoproliferative disorder
- Active malignancy
- History of cancer within 5 years prior to baseline except basal cell carcinoma, squamous cell carcinoma, ductal carcinoma in situ of the breast, carcinoma in situ of the uterine cervix, or thyroid cancer
- High risk of thrombosis or cardiovascular disease
- High risk of herpes zoster
- Active or recent infection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
Clinical Trial Site
Phoenix, Arizona, United States, 85006
Actively Recruiting
2
Clinical Trial Site
Portland, Oregon, United States, 97210
Actively Recruiting
3
Clinical Trial Site
Smyrna, Tennessee, United States, 37167
Actively Recruiting
4
Clinical Trial Site
Austin, Texas, United States, 78613
Actively Recruiting
5
Clinical Trial Site
Cedar Park, Texas, United States, 78613
Actively Recruiting
Research Team
C
Clinical Trial Administrator
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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