Actively Recruiting

Early Phase 1
Age: 18Years - 80Years
All Genders
Healthy Volunteers
NCT06189170

Phase I Study to Evaluate KP405 in Healthy and Parkinson's Disease Patients

Led by Kariya Pharmaceuticals · Updated on 2025-03-07

88

Participants Needed

1

Research Sites

86 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study will explore the safety, pharmacokinetics (PK) and pharmacodynamics (PD) of KP405 as a potential new treatment for Parkinson's disease.

CONDITIONS

Official Title

Phase I Study to Evaluate KP405 in Healthy and Parkinson's Disease Patients

Who Can Participate

Age: 18Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy as determined by a responsible physician through medical history, physical exam, ECG, Holter monitoring, and lab tests
  • Clinical diagnosis of Parkinson's disease meeting United Kingdom Brain Bank criteria
Not Eligible

You will not qualify if you...

  • History of significant physical or mental health issues interfering with study participation, excluding Parkinson's disease
  • Neurologic disorders other than Parkinson's disease, including stroke or transient ischemic attack within 12 months
  • Cognitive impairment
  • Seizure within 5 years
  • Head trauma with loss of consciousness within 6 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

MAC

Manchester, United Kingdom

Actively Recruiting

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Research Team

I

Ian Laquian, MBA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

TREATMENT

Number of Arms

11

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Phase I Study to Evaluate KP405 in Healthy and Parkinson's Disease Patients | DecenTrialz