Actively Recruiting

Phase 2
Age: 18Years - 80Years
All Genders
NCT07501702

A Phase 2 Study to Evaluate Povetacicept in Adults With Generalized Myasthenia Gravis

Led by Vertex Pharmaceuticals Incorporated · Updated on 2026-05-04

30

Participants Needed

6

Research Sites

150 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to evaluate the pharmacodynamic (PD) effect, safety, and tolerability of Povetacicept in participants with generalized myasthenia gravis (gMG).

CONDITIONS

Official Title

A Phase 2 Study to Evaluate Povetacicept in Adults With Generalized Myasthenia Gravis

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 to 80 years
  • Diagnosis of generalized myasthenia gravis with generalized muscle weakness
  • MGFA clinical classification II-IV
  • Additional inclusion criteria as defined in the protocol
Not Eligible

You will not qualify if you...

  • History of thymic surgery within 6 months of screening
  • History of malignancy within the last 5 years
  • Additional exclusion criteria as defined in the protocol

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 6 locations

1

Neurology Offices

Boca Raton, Florida, United States, 33428

Actively Recruiting

2

Homestead Associates in Research

Homestead, Florida, United States, 33033

Actively Recruiting

3

Quantix Research

Miami, Florida, United States, 33173

Actively Recruiting

4

Hawaii Pacific Neuroscience

Honolulu, Hawaii, United States, 96817

Actively Recruiting

5

Las Vegas Neurology Center

Las Vegas, Nevada, United States, 89106

Actively Recruiting

6

Clinical Trials of South Carolina - Neurology

Charleston, South Carolina, United States, 29406

Actively Recruiting

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Research Team

M

Medical Information

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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