Actively Recruiting

Phase 1
Age: 18Years +
All Genders
NCT05808634

Phase 1 Study Evaluating BA3182 in Patients With Advanced Adenocarcinoma.

Led by BioAtla, Inc. · Updated on 2025-09-25

168

Participants Needed

9

Research Sites

270 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objective of this study is to assess safety and efficacy of BA3182 in Advanced Adenocarcinoma

CONDITIONS

Official Title

Phase 1 Study Evaluating BA3182 in Patients With Advanced Adenocarcinoma.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically or cytologically confirmed locally advanced unresectable or metastatic adenocarcinoma
  • Age 18 years or older
  • Adequate kidney function
  • Adequate liver function
  • Adequate blood cell counts
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
Not Eligible

You will not qualify if you...

  • Clinically significant heart disease
  • Known uncontrolled central nervous system metastasis
  • Active or history of autoimmune disease
  • History of severe allergic reactions (Grade 3 or higher) to monoclonal antibody therapy or allergies to study agents
  • Incomplete recovery from major surgery or serious injury before first treatment dose
  • Known HIV infection, active hepatitis B, or hepatitis C
  • Pregnant or breastfeeding women

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 9 locations

1

UC Irvine

Irvine, California, United States, 92697

Actively Recruiting

2

USC Norris Comprehensive Cancer Center

Los Angeles, California, United States, 90033

Actively Recruiting

3

Yale Cancer Center

New Haven, Connecticut, United States, 06511

Actively Recruiting

4

Northwestern University

Chicago, Illinois, United States, 60611

Actively Recruiting

5

University of Illinois

Chicago, Illinois, United States, 60612

Actively Recruiting

6

Karmanos Cancer Institute

Detroit, Michigan, United States, 48201

Actively Recruiting

7

The Christ Hospital Cancer Center

Cincinnati, Ohio, United States, 45219

Actively Recruiting

8

University Hospitals Cleveland Medical Center

Cleveland, Ohio, United States, 44106

Actively Recruiting

9

Fred Hutch Cancer Center

Seattle, Washington, United States, 98109

Actively Recruiting

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Research Team

B

BioAtla Medical Affairs

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Phase 1 Study Evaluating BA3182 in Patients With Advanced Adenocarcinoma. | DecenTrialz