Actively Recruiting
A Phase 3 Study of HRS-8080 Versus Treatment Chosen by Physicians in Locally Advanced and Metastatic Breast Cancer
Led by Shandong Suncadia Medicine Co., Ltd. · Updated on 2026-01-26
240
Participants Needed
2
Research Sites
123 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is a multicenter, open-label, randomized controlled Phase 3 clinical trial. It is planned to enroll 240 female patients with locally advanced or metastatic breast cancer followed by disease progression after previous endocrine therapy.
CONDITIONS
Official Title
A Phase 3 Study of HRS-8080 Versus Treatment Chosen by Physicians in Locally Advanced and Metastatic Breast Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women aged 18 to 75 years old (including both values)
- ECOG Physical Strength Status (PS) of 0 to 1 point
- Histologically confirmed locally advanced or metastatic breast cancer
- Previously received 1 to 2 lines of endocrine therapy
- Expected survival longer than 6 months
- Adequate organ function
- Voluntary participation with informed consent and agreement to follow study procedures
You will not qualify if you...
- Rapid disease progression where endocrine therapy is unsuitable or intolerable
- History of severe clinical cardiovascular diseases
- Uncontrollable tumor-related pain as judged by investigators
- Severe infection within 4 weeks before study treatment
- Clinically significant endometrial abnormalities
- Untreated active hepatitis
- Known allergy to HRS-8080 components
- Pregnant or lactating women, or planning pregnancy during the study period
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Sun Yat-sen University Cancer Center
Guangzhou, Guangdong, China, 510000
Actively Recruiting
2
Hunan Cancer Hospital
Changsha, Hunan, China, 410000
Actively Recruiting
Research Team
M
Min Li
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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