Actively Recruiting
A Phase 2 Study of the Safety and Efficacy of Brepocitinib in Adults With Cutaneous Sarcoidosis (BEACON)
Led by Priovant Therapeutics, Inc. · Updated on 2025-05-18
28
Participants Needed
4
Research Sites
85 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will evaluate the clinical safety and efficacy of oral brepocitinib in participants with cutaneous sarcoidosis.
CONDITIONS
Official Title
A Phase 2 Study of the Safety and Efficacy of Brepocitinib in Adults With Cutaneous Sarcoidosis (BEACON)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 74 years
- Diagnosis of cutaneous sarcoidosis confirmed by characteristic skin biopsy
- A Cutaneous Sarcoidosis Activity and Morphology Instrument (CSAMI) activity score of 10 or higher
- Weight greater than 40 kg and less than 130 kg with a body mass index (BMI) under 40 kg/m2
You will not qualify if you...
- History of lymphoproliferative disorder
- Active malignancy
- History of cancer within 5 years before baseline, except basal cell carcinoma, squamous cell carcinoma, or carcinoma in situ of the uterine cervix
- High risk of thrombosis or cardiovascular disease
- High risk of herpes zoster
- Current or recent infection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Clinical Trial Site
San Francisco, California, United States, 94115
Actively Recruiting
2
Clinical Trial Site
Durham, North Carolina, United States, 27703
Actively Recruiting
3
Clinical Trial Site
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
4
Clinical Trial Site
Madison, Wisconsin, United States, 53715
Actively Recruiting
Research Team
C
Clinical Trial Administrator
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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