Actively Recruiting

Phase 1
Age: 18Years - 75Years
All Genders
NCT07038005

A Phase I Study of SPGL008 in Subjects With Advanced Malignant Tumors

Led by Shenyang Sunshine Pharmaceutical Co., LTD. · Updated on 2026-02-09

96

Participants Needed

1

Research Sites

96 weeks

Total Duration

On this page

Sponsors

S

Shenyang Sunshine Pharmaceutical Co., LTD.

Lead Sponsor

S

Shenzhen Sciprogen Bio-pharmaceutical Co., Ltd.

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study includes two cohorts, respectively evaluating safety, tolerability and preliminary efficacy of intravenous and subcutaneous administration of SPGL008.

CONDITIONS

Official Title

A Phase I Study of SPGL008 in Subjects With Advanced Malignant Tumors

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female aged 18 to 75 years
  • Histologically or cytologically confirmed advanced or metastatic malignant tumors
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
  • Expected survival of at least 3 months
  • Signed informed consent form
Not Eligible

You will not qualify if you...

  • Known uncontrolled or symptomatic central nervous system metastatic disease
  • Grade greater than 1 adverse events from previous anticancer therapy (except alopecia and fatigue)
  • Inadequate organ or bone marrow function
  • Pregnant or breastfeeding women
  • Known allergies, hypersensitivity, or intolerance to SPGL008

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Chongqing University Cancer Hospital

Chongqing, Chongqing Municipality, China, 400030

Actively Recruiting

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Research Team

Y

yongsheng Li

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

14

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A Phase I Study of SPGL008 in Subjects With Advanced Malignant Tumors | DecenTrialz