Actively Recruiting
Phenotyping Asthma for Bronchial Thermoplasty
Led by Massachusetts General Hospital · Updated on 2024-05-29
50
Participants Needed
2
Research Sites
185 weeks
Total Duration
On this page
Sponsors
M
Massachusetts General Hospital
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study will evaluate a new imaging technology, called optical coherence tomography (OCT) to examine the asthmatic airways before and after bronchial thermoplasty, which is a new treatment option for severe asthmatic patients. The aim of this study is to learn more about how airways respond to this new treatment. In the future the investigators hope OCT will aid clinicians in the initial assessment, management and long-term follow up of patients receiving bronchial thermoplasty.
CONDITIONS
Official Title
Phenotyping Asthma for Bronchial Thermoplasty
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient undergoing elective bronchial thermoplasty
- Patient is between the ages of 18 and 60
- Patient is able to give informed consent
- Negative pregnancy test for all females of childbearing potential who are sexually active and not using contraception, are seeking to become pregnant, or who are nursing
- Nonsmoking (less than 5 pack year tobacco exposure)
- No history of co-existing lung disease
- Meets American Thoracic Society criteria for diagnosis of asthma with either a bronchodilator response to albuterol (≥12% change in FEV1) or positive methacholine bronchoprovocation (PC20 < 25 mg/ml)
You will not qualify if you...
- Patients who are pregnant
- Patient does not meet the requirements to undergo clinical bronchial thermoplasty, as determined by the treating physician
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Actively Recruiting
2
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States, 02215
Actively Recruiting
Research Team
M
Melissa J Suter, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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