Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05855668

Phenotyping Patients With Alcohol and Cannabis Use Disorders Using the Addictions Neuroclinical Assessment

Led by Centre for Addiction and Mental Health · Updated on 2026-03-20

400

Participants Needed

1

Research Sites

263 weeks

Total Duration

On this page

Sponsors

C

Centre for Addiction and Mental Health

Lead Sponsor

C

Canadian Institutes of Health Research (CIHR)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This 2-arm study will recruit participants with 1) alcohol use disorder and 2) cannabis use disorder for a 12-week cognitive behavioral therapy, following a thorough baseline assessments on executive function, incentive salience, and negative emotionality.

CONDITIONS

Official Title

Phenotyping Patients With Alcohol and Cannabis Use Disorders Using the Addictions Neuroclinical Assessment

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient has been referred to or intends to participate in either the AUD or CUD Integrated Care Pathway and is willing to participate in group psychotherapy
  • Able to communicate and provide informed consent in English
  • 18 years of age or older
  • Willing and able to safely abstain from substances (except nicotine or tobacco) for 12 hours before eligibility and task assessments
  • Meets DSM-5 criteria for alcohol use disorder (AUD) or cannabis use disorder (CUD)
  • For AUD group: risky drinking defined as more than 10 drinks per week for females or more than 15 drinks per week for males on average over the past 30 days
  • For CUD group: daily or near-daily cannabis use over the past 30 days, defined as 4 or more days of cannabis use per week on average
Not Eligible

You will not qualify if you...

  • Active suicidal thoughts at the time of assessment
  • Suicide attempt within the past month
  • Unstable psychiatric or medical condition (e.g., acute psychosis or mania) or unstable use of another substance that may interfere with group participation (e.g., active fentanyl use)
  • Currently enrolled in another study that conflicts with this study's procedures or scientific integrity
  • Planning to be out of the province for a significant time during the treatment period

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Centre for Addiction and Mental Health

Toronto, Ontario, Canada, M6J 1H4

Actively Recruiting

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Research Team

K

Kelly Xiao, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

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