Actively Recruiting

Phase Not Applicable
Age: 21Years +
All Genders
Healthy Volunteers
NCT06747364

Phosphatidylethanol and Other Ethanol Consumption Markers

Led by The University of Texas Health Science Center at San Antonio · Updated on 2025-05-13

80

Participants Needed

2

Research Sites

229 weeks

Total Duration

On this page

Sponsors

T

The University of Texas Health Science Center at San Antonio

Lead Sponsor

N

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is intended to help the investigators understand how a biomarker found in the blood may be used to better identify the quantity and different patterns of alcohol use. The investigators hope that the results of this study will help identify the uses of alcohol-use markers in the blood in future alcohol prevention and treatment programs. It is hoped that the information learned from this study will benefit other people in the future. The study participants will come into the lab and will (1) consume alcohol in the lab designed to produce a peak blood alcohol concentration of 0.06% and have blood collected over 6 hours followed by abstinence for 10 days to give a small blood sample 4 times and (2) to give a small amount of blood 5 times within 28 days (naturalistic drinking) and provide answers about alcohol use.

CONDITIONS

Official Title

Phosphatidylethanol and Other Ethanol Consumption Markers

Who Can Participate

Age: 21Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Are 21 years old or older
  • Have a body mass index between 18 and 30 (height and weight proportionate)
  • Report drinking alcohol on more than one day in the past month, with at least one drinking day reaching a blood alcohol concentration of about 0.06%
Not Eligible

You will not qualify if you...

  • Have significant current or predicted alcohol withdrawal symptoms (CIWA-AR score of 10 or higher)
  • Are currently in alcohol treatment
  • Have a substance use disorder except for nicotine or caffeine
  • Have medical conditions contraindicating participation such as positive pregnancy test, scheduled surgery, or liver disease
  • Are currently breastfeeding
  • Have a DSM-5 psychiatric disorder with symptoms of psychosis or delirium
  • Are unable to understand the informed consent process or study instructions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

University of North Texas

Denton, Texas, United States, 76201

Actively Recruiting

2

University of Texas Health Science Center San Antonio

San Antonio, Texas, United States, 78229

Actively Recruiting

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Research Team

N

Nathalie Hill-Kapturczak, PhD

CONTACT

D

Donald Dougherty, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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