Actively Recruiting
Photo-medicine-Guided Dual Approach for Sentinel Lymph Node Reoperation in Locally Recurrent Breast Cancer Patients
Led by National Cancer Center, Korea · Updated on 2025-01-17
30
Participants Needed
1
Research Sites
124 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating a new technique to identify sentinel lymph nodes in patients with locally recurrent breast cancer. This study focuses on those who have had prior surgery on the same side and aims to improve the detection of these lymph nodes during reoperation. The study addresses the uncertainty about the role of sentinel lymph node biopsy (SLNB) in recurrent breast cancer and explores a method combining traditional radiotracer techniques with indocyanine green-fluorescence (ICG-F) to guide surgery. The study uses a photo-medicine-based dual localization approach for sentinel lymph node mapping during repeat SLNB (reSLNB). This technique combines standard radiotracer methods with ICG-F to enhance the detection rate of sentinel lymph nodes. The goal is to assess how well this combined method identifies sentinel lymph nodes, potentially reducing the need for more invasive procedures like axillary lymph node dissection. Participants will be female patients aged 18 or older with locally recurrent breast cancer who had previous axillary surgery. They will undergo sentinel lymph node biopsy using the dual localization technique during surgery. Researchers will evaluate the identification rate of sentinel lymph nodes on the day of surgery. The study also monitors participants' overall health and ability to consent, ensuring safety and appropriate follow-up during the clinical trial period.
CONDITIONS
Official Title
Photo-medicine-Guided Dual Approach for Reoperation of Sentinel Lymph Nodes in Locally Recurrent Breast Cancer Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with ipsilateral locally recurrent breast cancer who previously underwent ipsilateral axillary surgery.
- Female patients aged 18 years or older.
- Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.
- Patients who voluntarily decide to participate in the study and provide written informed consent.
You will not qualify if you...
- Patients with distant metastases.
- Patients who previously underwent ipsilateral mastectomy.
- Pregnant or breastfeeding women.
- Patients with a general condition that impairs the ability to understand or provide informed consent.
AI-Screening
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Trial Site Locations
Total: 1 location
1
National Cancer Center
Goyang-si, South Korea
Actively Recruiting
Research Team
S
SEEYOUN LEE
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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