Actively Recruiting

All Genders
NCT04428528

Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy

Led by Sunnybrook Health Sciences Centre · Updated on 2023-12-13

100

Participants Needed

1

Research Sites

626 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Our objective in this pilot study will be to identify PA parameters that can distinguish benign vs. malignant lesions, and also, if PA parameters change with within breast tumors during chemotherapy treatment over time.

CONDITIONS

Official Title

Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Must provide written informed consent before joining the study
  • Must be able and willing to follow safety procedures during scanning
  • Must be male or female between 20 and 80 years old at consent
  • For chemotherapy monitoring group: must be receiving neoadjuvant chemotherapy for locally advanced breast cancer
  • For chemotherapy monitoring group: must have biopsy-confirmed locally advanced breast cancer of any molecular subtype
  • For breast mass characterization group: must be referred to a breast diagnostic clinic for investigation of a breast mass
Not Eligible

You will not qualify if you...

  • Past medical history of abnormalities, significant injury, or procedures involving either breast except the lesion at issue
  • Any skin abnormalities like tattoos, open sores, or broken skin on either breast
  • Current or past connective tissue disease
  • Pregnant or lactating
  • Implanted electronic devices such as pacemakers, defibrillators, or neurological stimulators
  • History or expectation of significant anxiety related to diagnostic tests
  • History of musculoskeletal disease that may cause discomfort during scanning
  • Known sensitivity to low-power infrared radiation due to skin conditions
  • Any other condition judged by the investigator or research coordinator as unsuitable for study participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sunnybrook Health Sciences Centre

Toronto, Ontario, Canada, M4N3M5

Actively Recruiting

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Research Team

G

Gregory J Czarnota, PhD, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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