Actively Recruiting
Photoacoustic Tomography in Assessment of Lower Extremity Artery Disease
Led by Sun Yat-sen University · Updated on 2026-05-06
200
Participants Needed
1
Research Sites
217 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Lower extremity artery disease (LEAD) is characterized by low awareness rate and high missed diagnosis rate, leading to low treatment rate and high disabling mortality rate. However, none of the current examination methods can comprehensively and thoroughly evaluate the vascular structure and blood oxygen status of the lower extremity at the same time. Photoacoustic imaging can display millimeter-scale microvessels without the need for contrast agents. The investigators developed photoacoustic tomography (PACT) technology, which wass able to provide three-dimensional and high-resolution photoacoustic images of the target area.The investigators plan to recruit LEAD patients in different disease conditions and healthy volunteers to receive the PACT examination on the feet using this imaging system, and to evaluate the potential clinical role of the imaging system in LEAD, and its added value to current imaging methods.
CONDITIONS
Official Title
Photoacoustic Tomography in Assessment of Lower Extremity Artery Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- LEAD patients who agree to participate and provide informed consent
- Patients without LEAD confirmed by ultrasound and clinical diagnosis who agree to participate and provide informed consent
You will not qualify if you...
- Under 18 years of age
- Pregnant women, nursing mothers, or women planning pregnancy
- Contraindications for laser operation, such as photodynamic therapy in the last month
- Metal implants in lower legs or feet
- History of mental illness or abuse of drugs and alcohol
- Blood phobia or pathological low blood pressure
- History or risk of cerebral hemorrhage, peripheral vascular bleeding, or stroke
- Open wounds on lower legs or feet
- Unable or unwilling to cooperate with the study procedures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
the Third Affiliated Hospital of Sun Yat-sen University
Guangzhou, Guangdong, China, 510630
Actively Recruiting
Research Team
J
Jia Liu, Doctor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here