Actively Recruiting
Photoacoustic/Ultrasound Imaging in Patients of Dermatomyositis With Calcinosis Cutis: Characteristic Findings and Treatment Response Evaluation
Led by Peking Union Medical College Hospital · Updated on 2025-06-25
100
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Photoacoustic imaging (PAI) is an emerging biomedical modality that integrates the advantages of optical contrast and ultrasound imaging depth. Capable of providing morphological, functional, and molecular information, PAI shows significant promise for visualizing human superficial tissue. The goal of this clinical trial is to build a PAI evaluation method for DM skin lesions, explore its application value in assessing DM disease severity and evaluation of treatment response. The main questions it aims to answer are: 1. How to establish a non-invasive PA/US imaging evaluation method for DM skin lesions? 2. Can PAI precisely assess DM disease severity? 3. Can PAI systems predict the treatment response in DM with calcinosis cutis? Participants will receive regular PA/US imaging examinations during five stages of treatment (before treatment, 3 months, 6 months, 9 months and 12 months). And the effectiveness of PA/US in treatment response for DM at different time points will be evaluated.
CONDITIONS
Official Title
Photoacoustic/Ultrasound Imaging in Patients of Dermatomyositis With Calcinosis Cutis: Characteristic Findings and Treatment Response Evaluation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Fulfill the 2017 EULAR/ACR classification criteria for idiopathic inflammatory myositis
- Adult dermatomyositis patients with calcinosis included
- Patients with pathognomonic skin rashes classified as dermatomyositis or amyopathic dermatomyositis based on 2017 EULAR/ACR criteria
- Dermatomyositis diagnosis confirmed by muscle biopsy if no skin manifestations
- Amyopathic dermatomyositis patients grouped with dermatomyositis patients
- Calcinosis diagnosis based on clinical examination findings
You will not qualify if you...
- Disease onset before 18 years old
- Presence of overlap syndrome
- Diagnosis of inclusion body myositis (IBM)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Peking Union Medical College Hospital
Beijing, China
Actively Recruiting
Research Team
M
Meng Yang, Doctor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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